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") //-- login register international mouse phenotyping consortium advanced tools impress batch query impc publications browser phenoview rest api other tools about impc objectives and background impc members governance documentation coordination industry sponsors secretariat additional information arrive guidelines about ikmc impc privacy policy news & events events references using ikmc and impc resources contact my impc impc forum documentation communications materials produce and phenotype knockout mouse lines for 20,000 genes -- -- examples: cib2 , abnormal heart rate , bernard-soulier syndrome chrx:1234567-4567890 -- about impc what is impc? phenotyping pipeline what does impc do? how does impc work? how to explore? how to cite this resource? human diseases human diseases   -- rare human diseases phenotypic mouse models -- order models mouse lines es cells targeting vectors mouse lines es cells targeting vectors -- special reports embryo development sexual dimorphism cardiovascular hearing metabolism translating to other species genes phenotypes gene expression     -- advanced tools impress phenoview batch query parallel coordinates go annotations tool phenoview rest api data release statistics data download other tools -- more consortium publications all publications collaborator projects idg orthologs -- impc presentations embryonic lethal strains goes to biological systems page -- impc youtube channel contact / feedback news and events january 17, 2018 new diabetes genes discovered in latest impc research september 1, 2017 novel hearing loss genes identified in large study by scientists across the world june 26, 2017 study of unprecedented size reveals how sex ‘blindspot’ could misdirect medical research international mouse phenotype consortium the goal of the international mouse phenotyping consortium (impc) is to discover functional insight for every gene by generating and systematically phenotyping 20,000 knockout mouse strains. one of the most important tools at our scientific disposal in understanding mammalian gene function is the laboratory mouse. the fundamental genetic similarity between mice and humans allows researchers to infer a human gene's function based on studies with laboratory mice. one powerful technique is to turn off, or "knockout", the activity of a mouse gene to assess what biological systems are impacted. this gives insights how a similar gene in humans may contribute to disease when its activity is altered. the impc is generating a knockout mouse strain for every protein coding gene by using the embryonic stem cell resource generated by the international knockout mouse consortium (ikmc). the production of mouse strains from these es cells are tracked within the "international micro-injection tracking system" (imits) and are made available to the research community via public repositories. systematic broad-based phenotyping is performed by each impc center using standardized procedures found within the international mouse phenotyping resource of standardised screens (impress) resource. gene-to-phenotype associations are made by a versioned statistical analysis with all data freely available by this web portal and by several data download features. tweets by @impc gdpr-cookie-policy release : 7.0 ftp help/documenation license changelog -- © 2018 impc · international mouse phenotyping consortium legal notices --

URL analysis for mousephenotype.org

http://www.mousephenotype.org/about-impc/impc-members
http://www.mousephenotype.org/data/embryo
http://www.mousephenotype.org/data/biological-system/metabolism
https://www.mousephenotype.org/sites/mousephenotype.org/files/impc%20governance%20and%20coordination%20v02%20october%202014.pdf
http://www.mousephenotype.org/data/presentations
https://www.mousephenotype.org/data/batchquery
http://www.mousephenotype.org/my-impc/communications-materials
http://www.mousephenotype.org/impress/procedures/7
http://www.mousephenotype.org/data/release
http://www.mousephenotype.org/about-impc/impc-secretariat
http://www.mousephenotype.org/data/parallel
http://www.mousephenotype.org/data/alleleref#2
http://www.mousephenotype.org/impress
http://www.mousephenotype.org/data/alleleref
http://www.mousephenotype.org/data/documentation/aboutimpc#whatdoesimpcdo

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WHOIS LIMIT EXCEEDED - SEE WWW.PIR.ORG/WHOIS FOR DETAILS

  REFERRER http://www.pir.org/

  REGISTRAR Public Interest Registry

SERVERS

  SERVER org.whois-servers.net

  ARGS mousephenotype.org

  PORT 43

  TYPE domain

  REGISTERED unknown

DOMAIN

  NAME mousephenotype.org

NSERVER

  NS2.123-REG.CO.UK 62.138.132.21

  NS.123-REG.CO.UK 212.67.202.2

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